BDBM803553 US20260116884, Compound C036

SMILES CCN1CCC(n2cc(-c3c[nH]c4ncc(-c5cnn(C6CCN(C7CCC(NC(=O)c8ccc(Cl)c(N9CCC(=O)NC9=O)c8)CC7)CC6)c5)nc34)cn2)CC1

InChI Key InChIKey=LMZZOBNZMNMKHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803553   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Zhongmeihuadong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803553BDBM803553(US20260116884, Compound C036)
Affinity DataIC50: 3.70nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2026
Entry Details
US Patent