BDBM803559 US20260116884, Compound C042

SMILES CCN1CCC(n2cc(-c3c[nH]c4ncc(-c5ccc(OCCCNC(=O)c6cccc(N7CCC(=O)NC7=O)c6)c(C)c5)nc34)cn2)CC1

InChI Key InChIKey=YHXTYLUXEDJVTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803559   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Zhongmeihuadong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803559BDBM803559(US20260116884, Compound C042)
Affinity DataIC50: 2.10nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2026
Entry Details
US Patent