BDBM803686 2-((2-((1r,4r)-4-hydroxycyclohexyl)-6-methoxy-2H-indazol-5-yl)carbamoyl)-6-isopropylpyridine 1-oxide::US12617770, Compound 015

SMILES COc1cc2nn([C@H]3CC[C@H](O)CC3)cc2cc1NC(=O)c1cccc(C(C)C)[n+]1[O-]

InChI Key InChIKey=QIXQJUWZNFNPHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803686   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Wuhan Createrna Science and Technology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803686BDBM803686(2-((2-((1r,4r)-4-hydroxycyclohexyl)-6-methoxy-2H-i...)
Affinity DataIC50: 5.40nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent