BDBM803696 2-((6-(cyclopropylmethoxy)-2-((1r,4r)-4-hydroxycyclohexyl)-2H-indazol-5-yl)carbamoyl)-6-methylpyridine 1-oxide and Compound 292 2-((6-(cyclopropylmethoxy)-2-((1s,4s)-4-hydroxycyclohexyl)-2H-indazol-5-yl)carbamoyl)-6-methylpyridine 1-oxide::US12617770, Compound 019

SMILES Cc1cccc(C(=O)Nc2cc3cn([C@H]4CC[C@H](O)CC4)nc3cc2OCC2CC2)[n+]1[O-]

InChI Key InChIKey=FCNKPVABRVGKLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803696   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Wuhan Createrna Science and Technology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803696BDBM803696(2-((6-(cyclopropylmethoxy)-2-((1r,4r)-4-hydroxycyc...)
Affinity DataIC50: 8.10nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent