BDBM803698 2-((2-((1r,4r)-4-cyclopropyl-4-hydroxycyclohexyl)-6-methoxy-2H-indazol-5-yl)carbamoyl)-6-methylpyridine 1-oxide::US12617770, Compound 025

SMILES COc1cc2nn([C@H]3CC[C@@](O)(C4CC4)CC3)cc2cc1NC(=O)c1cccc(C)[n+]1[O-]

InChI Key InChIKey=APHXEHGXWLDVGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803698   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Wuhan Createrna Science and Technology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803698BDBM803698(2-((2-((1r,4r)-4-cyclopropyl-4-hydroxycyclohexyl)-...)
Affinity DataIC50: 13nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent