BDBM803725 N-(3-(3,3-dimethylbutyl)-4-oxo- 3,4-dihydroquinazolin-5-y1)-6- hydroxy-5-(4- methylpiperazin-1-yl)nicotinamide::US12617772, Example 4

SMILES O=C(Nc1cccc2ncn(Cc3ccccc3F)c(=O)c12)c1ccc(O)c(C(F)(F)F)n1

InChI Key InChIKey=AOKPSHIJWSGEDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803725   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandChemical structure of BindingDB Monomer ID 803725BDBM803725(N-(3-(3,3-dimethylbutyl)-4-oxo- 3,4-dihydroquinazo...)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent