BDBM803726 N-(2-((3,3- dimethylbutyl)carbamoyl) thiophen-3-y1)-5- hydroxy-6-(trifluoromethyl) picolinamide::US12617772, Example 5

SMILES CC(C)(C)CCNC(=O)c1sccc1NC(=O)c1ccc(O)c(C(F)(F)F)n1

InChI Key InChIKey=JHZPDEHOVBHIPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803726   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandChemical structure of BindingDB Monomer ID 803726BDBM803726(N-(2-((3,3- dimethylbutyl)carbamoyl) thiophen-3-y1...)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent