BDBM803727 5-hydroxy-N-(3-(2- methoxyphenethyl)-4-oxo- 3,4-dihydroquinazolin-5-yl)-6- (trifluoromethyl) picolinamide::US12617772, Example 6

SMILES COc1ccccc1CCn1cnc2cccc(NC(=O)c3ccc(O)c(C(F)(F)F)n3)c2c1=O

InChI Key InChIKey=KKOGXQFCXJSUCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803727   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandChemical structure of BindingDB Monomer ID 803727BDBM803727(5-hydroxy-N-(3-(2- methoxyphenethyl)-4-oxo- 3,4-di...)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent