BDBM803969 US20260124222, Compound I-177

SMILES O=C(Nc1ccnc(C(F)(F)F)c1)c1snc(-c2cncc3ccccc23)c1C1CC1

InChI Key InChIKey=YBOJSNPZEOZGDA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803969   

LigandChemical structure of BindingDB Monomer ID 803969BDBM803969(US20260124222, Compound I-177)
Affinity DataIC50: 400nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent