BDBM804033 US20260125365, Compound I-0281

SMILES O=c1[nH]cccc1Cn1c(=O)nc(Nc2cc3cn(CCO)nc3cc2Cl)n(Cc2cc(F)c(F)c(F)c2)c1=O

InChI Key InChIKey=UXAHEMLEUQGPCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804033   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804033BDBM804033(US20260125365, Compound I-0281)
Affinity DataIC50: 3.80nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent