BDBM804044 US20260125365, Compound I-0351

SMILES N#Cc1cc(Cn2c(Nc3ccc4c(c3)CCO4)nc(=O)n(-c3cncc4ccccc34)c2=O)ccc1F

InChI Key InChIKey=URYUJBNXYZOVGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804044   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804044BDBM804044(US20260125365, Compound I-0351)
Affinity DataIC50: 4.30nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent