BDBM804074 US20260125365, Compound II-0045

SMILES Cn1cnc(Cn2c(=O)nc(Nc3cc4cn(C)nc4cc3Cl)n(Cc3cc(F)c(F)c(Cl)c3)c2=O)n1

InChI Key InChIKey=OYGNKQSBYQNJRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804074   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804074BDBM804074(US20260125365, Compound II-0045)
Affinity DataIC50: 4.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent