BDBM804080 US20260125365, Compound II-0089

SMILES Cc1cncc(-n2c(=O)nc(Nc3cc4cn(CC(F)F)nc4cc3Cl)n(Cc3ccc(F)c(C#N)c3)c2=O)c1

InChI Key InChIKey=RPUDNDVHAPSBEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804080   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804080BDBM804080(US20260125365, Compound II-0089)
Affinity DataIC50: 3.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent