BDBM804085 US20260125365, Compound II-0118

SMILES CCn1cc2cc(Nc3nc(=O)n(-c4cncc(C)c4)c(=O)n3Cc3ccc(F)c(C#N)c3)c(Cl)cc2n1

InChI Key InChIKey=WWQDTPXJPZEWPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804085   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804085BDBM804085(US20260125365, Compound II-0118)
Affinity DataIC50: 4.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent