BDBM804167 US20260125365, Compound II-0571

SMILES Cc1cc(F)c(C#N)cc1Cn1c(Nc2ccc3nn(C)cc3c2)nc(=O)n(-c2cncc(Cl)c2)c1=O

InChI Key InChIKey=UFFZYHPRRWYXES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804167   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804167BDBM804167(US20260125365, Compound II-0571)
Affinity DataIC50: 5.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent