BDBM804181 US20260125365, Compound II-0132

SMILES Cn1cnc(Cn2c(=O)nc(Nc3cc4cn(CC(=O)N5CCOCC5)nc4cc3Cl)n(Cc3cc(Cl)c(F)cc3F)c2=O)n1

InChI Key InChIKey=GJFMOCQVIOXUOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804181   

TargetReplicase polyprotein 1a(2019-nCoV)
Shionogi & Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 804181BDBM804181(US20260125365, Compound II-0132)
Affinity DataIC50: 2.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent