BDBM804906 US20260125370, Compound 61

SMILES N=S1(=O)CCN(c2c(N(Cc3ncc(-c4nnc(C(F)F)o4)cc3F)c3ccccc3)c(=O)c2=O)CC1

InChI Key InChIKey=ZLHDVHVXHZKMDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 804906   

TargetHistone deacetylase 6(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 804906BDBM804906(US20260125370, Compound 61)
Affinity DataIC50: 29.8nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 804906BDBM804906(US20260125370, Compound 61)
Affinity DataIC50: 1.00E+4nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent