BDBM804985 US20260125372, Example 48

SMILES COC[C@H](C)Oc1cc(-c2cncs2)nc2ccc(NC(=O)C(C)C#N)cc12

InChI Key InChIKey=QJTURDHJJRESDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 804985   

TargetDynamin-1-like protein [1-699] and Mitochondrial dynamics protein MID49 [126-454](Human)
Astellas Engineered Small Molecules US

US Patent
LigandChemical structure of BindingDB Monomer ID 804985BDBM804985(US20260125372, Example 48)
Affinity DataIC50: 750nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/16/2026
Entry Details
US Patent