BDBM805044 US20260125375, Example C36

SMILES Cc1cc2c(-c3cccc([C@H](c4nncn4C)C4CCC4)c3)n[nH]c2c([C@H](C)N[C@H]2C[C@@H](O)C2)n1

InChI Key InChIKey=RNRQOKXGAYNIPR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 805044   

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805044BDBM805044(US20260125375, Example C36)
Affinity DataKi:  1.80nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805044BDBM805044(US20260125375, Example C36)
Affinity DataKi:  16.8nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent