BDBM805289 US20260125379, Compound A3

SMILES C[C@@H](OC(=O)C(C)(C)Oc1ccccc1/N=N/c1ccc(O)c(C(=O)O)c1)c1nc2cnc3[nH]ccc3c2n1N1CCC(CC#N)CC1

InChI Key InChIKey=LWLZCHPBVWNXNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 805289   

TargetTyrosine-protein kinase JAK1(Human)
E-Nitiate Biopharmaceuticals (Hangzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 805289BDBM805289(US20260125379, Compound A3)
Affinity DataIC50: 7.04nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
E-Nitiate Biopharmaceuticals (Hangzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 805289BDBM805289(US20260125379, Compound A3)
Affinity DataIC50: 102nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent