BDBM805298 US20260125379, Compound A12

SMILES CSCC1(C)CCN(n2c(CCO[N+](=O)[O-])nc3cnc4[nH]ccc4c32)CC1

InChI Key InChIKey=MAPVQPYSZNPMAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 805298   

TargetTyrosine-protein kinase JAK2(Human)
E-Nitiate Biopharmaceuticals (Hangzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 805298BDBM805298(US20260125379, Compound A12)
Affinity DataIC50: 37.9nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
E-Nitiate Biopharmaceuticals (Hangzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 805298BDBM805298(US20260125379, Compound A12)
Affinity DataIC50: 38.9nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent