BDBM805303 US20260125379, Compound B5

SMILES N#CC[C@H]1CC[C@H](n2c(N)nc3cnc4ccoc4c32)CC1

InChI Key InChIKey=APCNWFGSTVCBHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 805303   

TargetTyrosine-protein kinase JAK1(Human)
E-Nitiate Biopharmaceuticals (Hangzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 805303BDBM805303(US20260125379, Compound B5)
Affinity DataIC50: 1.33nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
E-Nitiate Biopharmaceuticals (Hangzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 805303BDBM805303(US20260125379, Compound B5)
Affinity DataIC50: 7.15nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent