BDBM805314 (S)-4-amino-N-methyl-N- (6-(trifluoromethyl)-2,3- dihydrobenzofuran-3-yl)- imidazo[1,5-a]quinox- aline-8-carboxamide::US20260125380, Example 107

SMILES CN(C(=O)c3ccc2nc(N)c1cncn1c2c3)[C@@H]5COc4cc(C(F)(F)F)ccc45

InChI Key InChIKey=RJCJMTTXIGGZEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805314   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805314BDBM805314((S)-4-amino-N-methyl-N- (6-(trifluoromethyl)-2,3- ...)
Affinity DataIC50: 4.50E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent