BDBM805316 (S)-4-amino-N-methyl-N- (6-(perfluoroethyl)-2,3- dihydrobenzofuran-3-yl)- imidazo[1,5-a]quinox- aline-8-carboxamide::US20260125380, Example 130

SMILES CN(C(=O)c1ccc2nc(N)c3cncn3c2c1)[C@@H]1COc2cc(C(F)(F)C(F)(F)F)ccc21

InChI Key InChIKey=IUYRFCZEZZSQGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805316   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805316BDBM805316((S)-4-amino-N-methyl-N- (6-(perfluoroethyl)-2,3- d...)
Affinity DataIC50: 1.36E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent