BDBM805317 (S)-4-amino-7-fluoro-N- (methyl-d3)-N-(6-(tri- fluoromethyl)-2,3-di- hydrobenzofuran-3-yl)- imidazo[1,5-a]quinox- aline-8-carboxamide::US20260125380, Example 41

SMILES [2H]C([2H])([2H])N(C(=O)c1cc3c(cc1F)nc(N)c2cncn23)[C@@H]5COc4cc(C(F)(F)F)ccc45

InChI Key InChIKey=MPJUJZTYGCAZPL-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805317   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805317BDBM805317((S)-4-amino-7-fluoro-N- (methyl-d3)-N-(6-(tri- flu...)
Affinity DataIC50: 8.16E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent