BDBM805524 US20260125391, Example 36

SMILES [2H]C([2H])(O)[C@@H]1[C@@H](C(F)(F)F)CN1C(=O)c1cn(C(C)C)c2cc(-c3nc(N[C@@H]4CCOC[C@H]4O)ncc3F)cc(F)c12

InChI Key InChIKey=PKTIQXBXXHYROB-KBMKNGFXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805524   

LigandChemical structure of BindingDB Monomer ID 805524BDBM805524(US20260125391, Example 36)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent