BDBM805528 US20260125391, Example 40

SMILES CO[C@]1(C)CN(C(=O)c2cn(C(C)C)c3cc(-c4nc(N[C@@H]5CCOC[C@H]5O)ncc4F)cc(F)c23)[C@@H]1CO

InChI Key InChIKey=HLUMGILTTGLBCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805528   

LigandChemical structure of BindingDB Monomer ID 805528BDBM805528(US20260125391, Example 40)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent