BDBM805563 (6-(5-Fluoro-2- (((3S,4R)-3- hydroxytetrahydro-2H- pyran-4- yl)amino)pyrimidin-4- yl)-1-methyl-1H-indol- 3-yl)((S)-2- ((methylsulfonyl)methyl) azetidin-1- yl)methanone::US20260125391, Example 75

SMILES Cn1cc(C(=O)N2CC[C@H]2CS(C)(=O)=O)c2ccc(-c3nc(N[C@@H]4CCOC[C@H]4O)ncc3F)cc21

InChI Key InChIKey=LDNBSYKMGLDRPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805563   

LigandChemical structure of BindingDB Monomer ID 805563BDBM805563((6-(5-Fluoro-2- (((3S,4R)-3- hydroxytetrahydro-2H-...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent