BDBM805569 ((2S,3S)-2- ((Cyclopropylsulfonyl) methyl)-3- methylazetidin-1-yl)(6- (5-fluoro-2-(((3S,4R)- 3-hydroxytetrahydro- 2H-pyran-4- yl)amino)pyrimidin-4- yl)-1-methyl-1H-indol- 3-yl)methanone::US20260125391, Example 81

SMILES C[C@H]1CN(C(=O)c2cn(C)c3cc(-c4nc(N[C@@H]5CCOC[C@H]5O)ncc4F)ccc23)[C@@H]1CS(=O)(=O)C1CC1

InChI Key InChIKey=WOVWUKVGHNJMAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805569   

LigandChemical structure of BindingDB Monomer ID 805569BDBM805569(((2S,3S)-2- ((Cyclopropylsulfonyl) methyl)-3- meth...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent