BDBM805584 ((3S,6S)-1,1-Difluoro- 6-(hydroxymethyl)-5- azaspiro[2.4]heptan-5- yl)(1-ethyl-6-(5-fluoro- 2-(((3S,4R)-3- hydroxytetrahydro-2H- pyran-4- yl)amino)pyrimidin-4- yl)-1H-indol-3- yl)methanone::US20260125391, Example 96

SMILES CCn1cc(C(=O)N2C[C@]3(C[C@H]2CO)CC3(F)F)c2ccc(-c3nc(N[C@@H]4CCOC[C@H]4O)ncc3F)cc21

InChI Key InChIKey=UWADGRHVHLQPET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805584   

LigandChemical structure of BindingDB Monomer ID 805584BDBM805584(((3S,6S)-1,1-Difluoro- 6-(hydroxymethyl)-5- azaspi...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
9/17/2026
Entry Details
US Patent