BDBM805587 (1,1-Difluoro-5- azaspiro[2.3]hexan-5- yl)(1-ethyl-6-(5-fluoro- 2-(((3S,4R)-3- hydroxytetrahydro-2H- pyran-4- yl)amino)pyrimidin-4- yl)-1H-indol-3- yl)methanone::US20260125391, Example 99

SMILES CCn1cc(C(=O)N2CC3(C2)CC3(F)F)c2ccc(-c3nc(N[C@@H]4CCOC[C@H]4O)ncc3F)cc21

InChI Key InChIKey=YQIDVAUGJOUEJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805587   

LigandChemical structure of BindingDB Monomer ID 805587BDBM805587((1,1-Difluoro-5- azaspiro[2.3]hexan-5- yl)(1-ethyl...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent