BDBM806400 US12624018, Compound 596

SMILES [2H]C([2H])([2H])C(n1cc(NC(=O)Cc2cc(C)c(Oc3ccnc4cc(F)c(C(=O)NC)cc34)cc2F)cn1)(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI Key InChIKey=IAODGSSZDWCHFL-WVZRYRIDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 806400   

LigandChemical structure of BindingDB Monomer ID 806400BDBM806400(US12624018, Compound 596)
Affinity DataIC50: 0.700nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Odyssey Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 806400BDBM806400(US12624018, Compound 596)
Affinity DataIC50: 2.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent