BDBM806472 US12624028, Compound 75

SMILES COc1cc(C(=O)O)ccc1Oc5nc(C2CCOCC2)c(c3ccc(F)cc3)c6cc4cn[nH]c4cc56

InChI Key InChIKey=MLRKNNOLPLHEOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 806472   

TargetAlpha-1-antitrypsin/Neutrophil elastase(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 806472BDBM806472(US12624028, Compound 75)
Affinity DataIC50: 2.08E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent