BDBM806536 US12624028, Compound 176

SMILES CC(C)c4c(O[C@@H]1C[C@@H](C(=O)O)C1)nc3cc2[nH]ncc2cc3c4c5ccc(F)cc5

InChI Key InChIKey=WIUFLMRLYLTYGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 806536   

TargetAlpha-1-antitrypsin/Neutrophil elastase(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 806536BDBM806536(US12624028, Compound 176)
Affinity DataIC50: 2.08E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent