BDBM806592 (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-3-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propionamide::US12624050, Example 1::US12630561, Example 10

SMILES C[C@H](Nc1ccc2c(c1)OCCn1c-2nc(N2C(=O)OC[C@H]2C(F)F)c1F)C(N)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 806592   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangsu Hansoh Pharmaceutical Group Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 7.90nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangsu Hansoh Pharmaceutical Group Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 7.90nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Jiangsu Hansoh Pharmaceutical Group Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 1.40E+3nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Jiangsu Hansoh Pharmaceutical Group Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 1.79E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 1.79E+3nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806592BDBM806592((S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent