BDBM806601 (S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-1-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propionamide::US12624050, Example 46::US12630561, Example 97

SMILES C[C@H](Nc1ccc2c(c1)OCCn1cc(N3C(=O)CC[C@H]3C(F)F)nc1-2)C(N)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 806601   

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 2.10nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 2.10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 190nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 190nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 510nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 510nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 1.65E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806601BDBM806601((S)-2-((2-((S)-2-(difluoromethyl)-5-oxopyrrolidin-...)
Affinity DataIC50: 1.65E+3nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent