BDBM806639 (3S,4R)-4-((7-(1H- Pyrazol-4- yl)quinazolin-2- yl)amino)tetrahydro- 2H-pyran-3-ol::US20260132122, Example 31

SMILES O[C@@H]1COCC[C@H]1Nc1ncc2ccc(-c3cn[nH]c3)cc2n1

InChI Key InChIKey=GCUAPQZKSZVGDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 806639   

LigandChemical structure of BindingDB Monomer ID 806639BDBM806639((3S,4R)-4-((7-(1H- Pyrazol-4- yl)quinazolin-2- yl)...)
Affinity DataIC50: 10nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806639BDBM806639((3S,4R)-4-((7-(1H- Pyrazol-4- yl)quinazolin-2- yl)...)
Affinity DataIC50: 550nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent