BDBM806659 (3R,4R)-4-((7-(1- Cyclopropyl-1H- imidazol-5- yl)quinazolin-2- yl)amino)-1- (methylsulfonyl) piperidin-3-ol::US20260132122, Example 51

SMILES CS(=O)(=O)N1CC[C@@H](Nc2ncc3ccc(-c4cncn4C4CC4)cc3n2)[C@H](O)C1

InChI Key InChIKey=XUXZODGJEFNZFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 806659   

LigandChemical structure of BindingDB Monomer ID 806659BDBM806659((3R,4R)-4-((7-(1- Cyclopropyl-1H- imidazol-5- yl)q...)
Affinity DataIC50: 10nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 806659BDBM806659((3R,4R)-4-((7-(1- Cyclopropyl-1H- imidazol-5- yl)q...)
Affinity DataIC50: 10nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent