BDBM806947 (3R)-1-ethyl-4-[2-(2-fluorophenyl)sulfonyl-2-azaspiro[3.3]heptan-6-yl]-3-methyl-2,3-dihydropyrido[3,2-e][1,4]diazepin-5-one::US20260132127, Example 245

SMILES CCN1C[C@@H](C)N(C2CC3(C2)CN(S(=O)(=O)c2ccccc2F)C3)C(=O)c2ncccc21

InChI Key InChIKey=BBXJLPPKQJBFRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 806947   

TargetThyrotropin-releasing hormone-degrading ectoenzyme(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 806947BDBM806947((3R)-1-ethyl-4-[2-(2-fluorophenyl)sulfonyl-2-azasp...)
Affinity DataIC50: 2nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent