BDBM807262 N-benzyl-1-(3-chlorophenyl)-6-(2-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide::US20260132132, Example 1107

SMILES O=C(NCc1ccccc1)c1nn(-c2cccc(Cl)c2)c2c1CCN(c1ccc3c(c1)CN(CCO)CC3)C2=O

InChI Key InChIKey=SWJHYOGONXDQGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 807262   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807262BDBM807262(N-benzyl-1-(3-chlorophenyl)-6-(2-(2-hydroxyethyl)-...)
Affinity DataIC50: 55nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent