BDBM807313 (R)-1-(3-chlorophenyl)-6-(2-ethyl-4-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)-N-((4-methylpyridin-3-yl)methyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide::US20260132132, Example 1158

SMILES CCN1Cc2cc(N3CCc4c(C(=O)NCc5cnccc5C)nn(-c5cccc(Cl)c5)c4C3=O)ccc2[C@@H](C)C1

InChI Key InChIKey=XTGXPAYCRMIMIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807313   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807313BDBM807313((R)-1-(3-chlorophenyl)-6-(2-ethyl-4-methyl-1,2,3,4...)
Affinity DataIC50: 55nMAssay Description:Recombinant KRAS G12C (amino acids 1-169, SEQ ID NO:1), KRAS G12D (amino acids 1-169, SEQ ID NO:2), KRAS G12V (amino acids 1-169, SEQ ID NO:3) and SO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetCoagulation factor X(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807313BDBM807313((R)-1-(3-chlorophenyl)-6-(2-ethyl-4-methyl-1,2,3,4...)
Affinity DataIC50: 2.50E+4nMAssay Description:Recombinant KRAS G12C (amino acids 1-169, SEQ ID NO:1), KRAS G12D (amino acids 1-169, SEQ ID NO:2), KRAS G12V (amino acids 1-169, SEQ ID NO:3) and SO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent