BDBM807317 1-(3-chlorophenyl)-6-(2-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)-7-oxo-N-((4-(trifluoromethyl)pyridin-3-yl)methyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide::US20260132132, Example 1162

SMILES O=C(NCc1cnccc1C(F)(F)F)c1nn(-c2cccc(Cl)c2)c2c1CCN(c1ccc3c(c1)CN(CCO)CC3)C2=O

InChI Key InChIKey=VNDXQDJCMRFOPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 807317   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807317BDBM807317(1-(3-chlorophenyl)-6-(2-(2-hydroxyethyl)-1,2,3,4-t...)
Affinity DataIC50: 55nMAssay Description:Recombinant KRAS G12C (amino acids 1-169, SEQ ID NO:1), KRAS G12D (amino acids 1-169, SEQ ID NO:2), KRAS G12V (amino acids 1-169, SEQ ID NO:3) and SO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent