BDBM807325 1-(3-chlorophenyl)-6-(2-(2-hydroxyethyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)-N-((2-methylpyridin-4-yl)methyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide::US20260132132, Example 1171

SMILES Cc1cc(CNC(=O)c2nn(-c3cccc(Cl)c3)c3c2CCN(c2ccc4c(c2)CN(CCO)CC4)C3=O)ccn1

InChI Key InChIKey=AODAACUPRYKGOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 807325   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807325BDBM807325(1-(3-chlorophenyl)-6-(2-(2-hydroxyethyl)-1,2,3,4-t...)
Affinity DataIC50: 55nMAssay Description:Recombinant KRAS G12C (amino acids 1-169, SEQ ID NO:1), KRAS G12D (amino acids 1-169, SEQ ID NO:2), KRAS G12V (amino acids 1-169, SEQ ID NO:3) and SO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent