BDBM807526 1-(3-chlorophenyl)-N-((1,5-dimethyl-1H-pyrazol-3-yl)methyl)-6-(4-(3-hydroxypropyl)-5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide::US20260132132, Example 1377

SMILES Cc1cc(CNC(=O)c2nn(-c3cccc(Cl)c3)c3c2CCN(c2ccc4c(c2)C(=O)N(CCCO)CCO4)C3=O)nn1C

InChI Key InChIKey=TWPKMKAFNGYVBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807526   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807526BDBM807526(1-(3-chlorophenyl)-N-((1,5-dimethyl-1H-pyrazol-3-y...)
Affinity DataIC50: 55nMAssay Description:Recombinant KRAS G12C (amino acids 1-169, SEQ ID NO:1), KRAS G12D (amino acids 1-169, SEQ ID NO:2), KRAS G12V (amino acids 1-169, SEQ ID NO:3) and SO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetCoagulation factor X(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 807526BDBM807526(1-(3-chlorophenyl)-N-((1,5-dimethyl-1H-pyrazol-3-y...)
Affinity DataIC50: 6.50E+3nMAssay Description:Table 8: In vitro inhibition of related proteases was determined using a single-concentration % inhibition screen and/or IC50 determination at releva...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent