BDBM807527 1-(3-chlorophenyl)-N-((5-methyl-1H-pyrazol-3-yl)methyl)-7-oxo-6-(5-oxo-4-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide::US20260132132, Example 1378
SMILES Cc1cc(CNC(=O)c2nn(-c3cccc(Cl)c3)c3c2CCN(c2ccc4c(c2)C(=O)N(CC(F)(F)F)CCO4)C3=O)n[nH]1
InChI Key InChIKey=ZBSGKGLQBYPXSR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 807527
Affinity DataIC50: 55nMAssay Description:Recombinant KRAS G12C (amino acids 1-169, SEQ ID NO:1), KRAS G12D (amino acids 1-169, SEQ ID NO:2), KRAS G12V (amino acids 1-169, SEQ ID NO:3) and SO...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Table 8: In vitro inhibition of related proteases was determined using a single-concentration % inhibition screen and/or IC50 determination at releva...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Table 8: In vitro inhibition of related proteases was determined using a single-concentration % inhibition screen and/or IC50 determination at releva...More data for this Ligand-Target Pair