BDBM807698 2-((2-Fluoro-4-(trifluoromethyl)benzyl)thio)-3-(5-hydroxypyrazin-2-yl)pyrazolo[5,1-f][1,2,4]triazin-4(3H)-one::US20260132136, Example 28

SMILES O=c1c2ccnn2nc(SCc2ccc(C(F)(F)F)cc2F)n1-c1cnc(O)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 807698   

TargetNADPH oxidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807698BDBM807698(2-((2-Fluoro-4-(trifluoromethyl)benzyl)thio)-3-(5-...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 3(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807698BDBM807698(2-((2-Fluoro-4-(trifluoromethyl)benzyl)thio)-3-(5-...)
Affinity DataIC50: 5.30E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807698BDBM807698(2-((2-Fluoro-4-(trifluoromethyl)benzyl)thio)-3-(5-...)
Affinity DataIC50: 6.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 5(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807698BDBM807698(2-((2-Fluoro-4-(trifluoromethyl)benzyl)thio)-3-(5-...)
Affinity DataIC50: 8.90E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetCytochrome b-245 heavy chain(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807698BDBM807698(2-((2-Fluoro-4-(trifluoromethyl)benzyl)thio)-3-(5-...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent