BDBM807828 2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyridin-3-yl)-5-methylpyrazolo[5,1-f][1,2,4]triazin-4(3H)-one::US20260132136, Example 158

SMILES Cc1cnn2nc(SCc3ccc(Cl)cc3)n(-c3cnc(O)c(F)c3)c(=O)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 807828   

TargetNADPH oxidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807828BDBM807828(2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyri...)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807828BDBM807828(2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyri...)
Affinity DataIC50: 6.10E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetCytochrome b-245 heavy chain(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807828BDBM807828(2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyri...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 3(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807828BDBM807828(2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyri...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 5(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807828BDBM807828(2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyri...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent