BDBM807916 (R)-5-((1-(4-(3- (Dimethylamino) pyrrolidin-1-yl)-3- fluorophenyl)-1H- imidazol-4- yl)amino)pyrazine-2- carbonitrile::US20260132140, Example 79

SMILES CN(C)[C@@H]1CCN(c2ccc(-n3cnc(Nc4cnc(C#N)cn4)c3)cc2F)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807916   

TargetSerine/threonine-protein kinase Chk1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807916BDBM807916((R)-5-((1-(4-(3- (Dimethylamino) pyrrolidin-1-yl)-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807916BDBM807916((R)-5-((1-(4-(3- (Dimethylamino) pyrrolidin-1-yl)-...)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent