BDBM807990 (R)-5-((1-(4-(3- Aminopyrrolidin-1- yl)phenyl)-1H- imidazol-4- yl)amino)pyrazine-2- carbonitrile::US20260132140, Example 153

SMILES N#Cc1cnc(Nc2cn(-c3ccc(N4CC[C@@H](N)C4)cc3)cn2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 807990   

TargetSerine/threonine-protein kinase Chk1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 807990BDBM807990((R)-5-((1-(4-(3- Aminopyrrolidin-1- yl)phenyl)-1H-...)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807990BDBM807990((R)-5-((1-(4-(3- Aminopyrrolidin-1- yl)phenyl)-1H-...)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent