BDBM807992 (R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phenyl)-1H- imidazol-4- yl)amino) pyrazine-2-carbonitrile::US20260132140, Example 155

SMILES CN[C@@H]1CCN(c2ccc(-n3cnc(Nc4cnc(C#N)cn4)c3)cc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 807992   

TargetSerine/threonine-protein kinase Chk1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-2 (RSK3)(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 822nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-3(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 1.12E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-6(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 1.96E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 3.42E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 807992BDBM807992((R)-5-((1-(4-(3- (Methylamino)pyrrolidin- 1-yl)phe...)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent